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On October 15, 2024, Brazil's Senate approved Bill No. 6120 of 2019, a REACH-like chemical management bill aimed at establishing a national registry of chemical substances. This bill mandates a comprehensive assessment and risk control of chemicals used, produced, or imported within the country to minimize adverse impacts on human health and the environment.

On September 26, 2023, the Commission on Constitution, Justice and Citizenship (CCJC) in Brazil published PL 6120/2019. Eariler on May 9, 2023, CCJC approved the bill (PL 6120/2019) and has send it to the Federal Senate for further consideration. PL 6120/2019 proposes to set up a national chemical inventory as a national database to collect the information on chemicals imported or manufactured in Brazil with hazard characteristics. If PL 6120/2019 is approved, Brazil will be the fourth country in South America that have chemical management regulations, following Peru, Chile, and Colombia.

Earlier in 2019, PL 6120/2019 was submitted to establish a national inventory of chemicals and collect information of chemicals manufactured in or imported to Brazil. However, substantial progress was not made. Currently, the bill has been transferred to the Federal Senate for further approval. If the bill successfully passes and becomes a law, Brazil will adopt a national chemical inventory system which covers official assessment of substance risks, the publication of authorized substance lists, and the clarification of enforcement agencies.

On November 23, 2022, Bill PL 6120/2019 was approved by the Commission of Economic Development, Industry, Trade, and Commercial Services (CDEICS) of the Brazilian Chamber of Deputies and has been submitted to the Commission on Constitution, Justice and Citizenship (CCJS) for further review. If the Bill successfully passes the review, it will act as the Brazilian REACH Regulation. Domestic enterprises involved in exporting chemicals to Brazil should pay close attention to the Bill. If the Bill becomes law, Brazil will become the third country in South America, to set up chemical management rules, after Chile and Colombia.